Benzenesulphonamide derivatives
AssigneeJohn Wyeth & Brother Limited
InventorJohn T. A. Boyle
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Abstract
Compounds having the formula ##STR1## wherein X.sub.1 and X.sub.2 are independently hydrogen, halogen, trifluoromethyl, lower alkyl or lower alkoxy; X.sub.3 is halogen or trifluoromethyl; one of A and B is CH and the other is CH or N and their pharmaceutically acceptable acid addition salts are useful as pharmaceuticals, in particular as anti-hypertensive agents. Novel 1-[4-(amino or nitro)benzenesulphonyl]-4-benzoylpiperazines are also disclosed as intermediate compounds.
Claims1
A compound selected from these having the formula I ##STR18## and, in the case where R is amino, their acid addition salts, wherein R is selected from amino and nitro and X.sub.1 and X.sub.2 are independently selected from hydrogen, halogen, trifluoromethyl, lower alkyl and lower alkoxy.
Dependencies are inferred from the claim text.