Process for producing L-glutamic acid by fermentation
AssigneeKyowa Hakko Kogyo Co., Ltd.
InventorsKiyoji Hattori, Yukinobu Kotani, Kuniki Kino
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Abstract
A process is disclosed for producing L-glutamic acid, the process involves culturing a microorganism belonging to the genus Corynebacterium or Brevibacterium and having both an ability to produce L-glutamic acid and a resistance to .alpha.-naphthoquinoline, an antibiotic inhibiting energy metabolism or a precursor for ubiquinone biosynthesis in a nutrient medium until L-glutamic acid is accumulated in the resulting culture liquor, and recovering the L-glutamic acid therefrom.
Claims6
A process for producing L-glutamic acid, which comprises culturing a microorganism belonging to the genus Corynebacterium or Brevibacterium which has both an ability to produce L-glutamic acid and a resistance to 100 .mu.g/ml .alpha.-naphthoquinoline, 100 .mu.g/ml oligomycin, or 2 mg/ml p-hydroxycinnamate in a nutrient medium until L-glutamic acid is accumulated in the culture liquor, and thereafter recovering the L-glutamic acid therefrom.
A biologically pure culture of the microorganism Corynebacterium glutamicum having the identifying characteristics of a member selected from a group consisting of NRRL B-15531, FERM BP-428 and FERM BP-430 which culture possesses the ability to produce L-glutamic acid.
A biologically pure culture of the microorganism Brevibacterium lactofermentum having the identifying characteristics of a member selected from a group consisting of NRRL B-15530, FERM BP-429 and FERM BP-431 which culture possesses the ability to produce L-glutamic acid.
Dependencies are inferred from the claim text.