Retro-inverted peptides analogues of Bradykinin Potentiator BPP.sub.5a

Retro-inverted peptides which are analogues of Bradykinin Potentiating Pentapeptide having the general formula:

• ##STR7## effective as antihypertensives and, resistant to angiotensin conversion enzyme, wherein:
• R.sup.3 is D-Lysine, R.sup.2 is D-Phenylanine and
• R.sup.1 represents the side chain of aminoacid residues present in the chains of natural peptides;
• A and B, taken together, are a --(CH.sub.2).sub.m --residue closed to form a ring on the nitrogen and caron atoms to which they are bonded, with one carbon atom of the --(CH.sub.2pl ).sub.m --bridge being directly bonded to an o-benzyl or to an -S-phenyl group;
• m is equal to 3 or 4;
• and
• z represents a hydroxy, alkylhydroxy or amino group.