Aqueous liquid preparation
AssigneesTakeda Chemical Industries, Ltd., Senju Pharmaceutical Co., Ltd.
InventorsHisayoshi Shimizu, Mitsuaki Oshima, Hideo Terayama
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Abstract
In the aqueous liquid preparation of this invention, which comprises a compound of the formula; ##STR1## wherein R is an alkyl having 1-6 carbon atoms, and at least one species of the solubilizers selected from the group consisting of polyvinylpyrrolidone, cyclodextrin and caffeine, the solubility of the compound in water can be heightened and the aqueous liquid prepared thereby can afford a desired stability and mitigate eye-irritation or nose-irritation.
Claims12
An aqueous liquid composition, which comprises a therapeutically effective amount of a compound of the formula;
- ##STR3## wherein R is an alkyl having 1-6 carbon atoms, and at least one solubilizer selected from the group consisting of polyvinylpyrrolidone in an amount of about 0.2-20% (W/V), cyclodextrin in an amount of about 0.2-5% (W/V), and caffeine in an amount of about 0.1-2% (W/V).
Dependencies are inferred from the claim text.