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US 4,727,181 AGranted
Process for the preparation of .alpha.-halocinnamate esters
AssigneeThe Dow Chemical Company
InventorWilliam J. Kruper, Jr.
Life of this patent
Estimating the term…
Abstract
Prepare esters of .alpha.-halocinnamic acid and related compounds in high yield under relatively mild conditions.
Claims20
A process comprising contacting a hydroxyl compound of the formula ROH, wherein R is an aromatic or aliphatic hydrocarbon moiety, and a 1,1-dihalo-1-alkene in the presence of an acid catalyst under reaction conditions such that there is formed a carboxylic acid ester of the formula:
- ##STR5## wherein Q is halo, hydrogen, alkyl, haloalkyl, aromatic or substituted aromatic;
- R.sub.a and R.sub.b are independently hydrogen, haloalkyl, aromatic or substituted aromatic wherein the substituents are electron withdrawing or electron donating moieties;
- and R is an aromatic or aliphatic hydrocarbon moiety.
A process comprising contacting in the presence of an acid catalyst a compound of the formula:
- ##STR6## wherein each X is halo;
- Q is halo, hydrogen, alkyl, haloalkyl, aromatic or substituted aromatic wherein the substituents are electron withdrawing or electron donating moieties;
- L is a readily polarizable leaving moiety;
- R.sub.a and R.sub.b are independently hydrogen, haloalkyl, aromatic or substituted aromatic wherein the substituents are electron withdrawing or electron donating moieties;
- with an alcohol of the formula ROH, wherein R is aromatic or aliphatic, under reaction conditions such that there is formed a compound of the formula:
- ##STR7##
3 more elements
Dependencies are inferred from the claim text.