Human immune interferon
AssigneeGenentech, Inc.
InventorsDavid V. Goeddel, Patrick Gray
Life of this patent
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Abstract
Disclosed is a complete description of the preparation of novel, substantially pure polypeptide via recombinant DNA techniques utilizing any of an assortment of expression vectors and host cultures. The polypeptide, human immune (gamma) interferon (IFN-.gamma.), is isolated and characterized in terms of DNA and amino acid sequences, physical attributes and biological activity.
Claims5
A DNA molecule comprising a recombinant DNA molecule or a cDNA molecule encoding a polypeptide comprising the amino acid sequence:
- ##STR3##
A DNA molecule comprising a recombinant DNA molecule or a cDNA molecule encoding a polypeptide comprising the amino acid sequence:
- ##STR4##
A molecule consisting essentially of a DNA molecule encoding the amino acid sequence of recombinant human immune interferon.
A molecule consisting essentially of a DNA molecule encoding the amino acid sequence of des-CYS-TYR-CYS recombinant human immune interferon.
Dependencies are inferred from the claim text.