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US 4,727,077 AGranted
Benzoyl urea compounds, process for their production, and antitumorous compositions containing them
AssigneeIshihara Sangyo Kaisha, Ltd.
InventorsTakahiro Haga, Nobutoshi Yamada, Hideo Sugi, Toru Koyanagi, Nobuo Kondo, Tsunetaka Nakajima, Masahiro Watanabe, Kazumasa Yokoyama
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Abstract
A benzoyl urea compound having the formula: ##STR1## wherein A is a bromine atom or a chlorine atom.
Claims10
A benzoyl urea compound having the formula:
- ##STR16## wherein A is a bromine atom or a chlorine atom.
An antitumorous composition comprising:
- an antitumorously effective amount of a benzoyl urea compound having the formula:
- ##STR17## where A is a bromine atom or a chlorine atom and a pharmaceutically acceptable adjuvant.
A method of treating a cancer resulting from the growth of P-388 leukemia cells, L-1210 leukemia cells, B-16 melanoma cells and M-5074 ovarium sarcoma cells, comprising:
- administering to a host subject suffering from said cancer an antitumorously effective amount of a benzoyl urea compound of the formula:
- ##STR18## wherein A is bromine or chlorine.
Dependencies are inferred from the claim text.