Urine specimen maintenance formula
AssigneeBecton, Dickinson and Company
InventorsJayraj S. Desai, Jack J. Mehl
Life of this patent
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Abstract
A urine specimen maintenance formulation is provided which, when the urine specimen is added, maintains the specimen in the desired unaltered form for subsequent testing, without the need for refrigeration or other preservation measures, while simultaneously preventing any additional bacterial growth in the specimen. The formula of the invention includes distilled water, mannitol, boric acid and sodium borate. Additionally, the formula may include a buffer, such as sodium acetate, glutamine or other amino acids, and a surface active or dispersing agent to facilitate concentration of cellular elements during subsequent centrifugation of the sample for microscopic examination, as well as to facilitate preservation of organisms.
Claims16
A liquid composition for the bacteriostatic maintenance of urine specimens, comprising
- (a) boric acid;
- (b) sodium borate;
- (c) water;
- (d) mannitol;
- (e) said boric acid, said sodium borate, said water and said mannitol being present in amounts effective for providing a maintenance composition for a urine sample;
- and
- (f) said boric acid, said sodium borate and said mannitol being dissolved in the said composition to provide within the range of between about 0.45 and 0.55 percent boric acid, within the range of between about 1.08 and 1.32 percent sodium borate, and within the range of between about 0.9 and 1.1 percent mannitol in a urine sample.
A bacteriostatic liquid maintenance composition for urine, comprising
- (a) boric acid present in said composition in an amount within the range of between about 4.5 and 5.5 grams;
- (b) sodium borate present in said composition within the range of between about 10.8 and 13.2 grams;
- (c) distilled water present in said composition within the range of between about 85 and 115 milliliters;
- and
- (d) mannitol present in said composition within the range of between about 9 and 11 grams.
A bacteriostatic maintenance composition consisting essentially of
- (a) distilled water within the range of between about 85 and 115 milliliters;
- (b) 5 grams of boric acid;
- (c) 12 grams of sodium borate;
- and
- (d) 10 grams of mannitol.
Dependencies are inferred from the claim text.