Anti-bacterial feedstuff compositions and process for preparing the same

A method for treating gastro-intestinal infections in mammals comprising introducing into the gastro-intestinal tract an effective amount of an anti-bacterial composition which comprises:

• (a) a sufficient amount of a thiocyanate to give a thiocyanate concentration in the gastro-intestinal tract of at least 0.1 mM;
• (b) a sufficient amount of hydrogen peroxide donor to give hydrogen peroxide concentration in the gastro-intestinal tract of at least 0.1 mM;
• and
• (c) lactoferrin and lactoperoxidase wherein the weight ratio of lactoferrin to lactoperoxidase is from about 2:1 to about 60:1 respectively.

Foodstuff composition comprising:

• (a) lactoperoxidase in an amount of at least 1 mg/kg of the total composition;
• (b) lactoferrin in an amount of at least 10 mg/kg of the total conposition;
• (c) thiocyanate in an amount of at least 16 ppm of the total composition;
• and
• (d) a peroxide donor in an effective amount of at least 21 ppm of the total composition.

Animal feedstuff composition comprising:

• (a) lactoperoxidase in an amount of at least 1 mg/kg of the total composition;
• (b) lactoferrin in an amount of at least 10 mg/kg of the total composition;
• (c) thiocyanate in an amount of at least about 16 ppm of the total composition;
• and
• (d) a peroxide donor in an effective amount of at least 21 ppm of the total composition.