Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
AssigneeUSV Pharmaceutical Corporation
InventorsUtpal R. Chakraborty, Raymond D. Youssefyeh
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AssigneeUSV Pharmaceutical Corporation
InventorsUtpal R. Chakraborty, Raymond D. Youssefyeh
Estimating the term…
The present invention is concerned with the therapeutic composition comprising as an active ingredient a compound of the formula: (R.sub.1)(R.sub.2) Ar--Z--M--Ar.sub.1 (R.sub.3)(R.sub.4) I and salts thereof; wherein Ar and Ar.sub.1 are independently phenyl, naphthyl or a nitrogen, oxygen, or sulfur heterocyclic ring; Z is an alkylene chain containing from 1 to 5 carbon atoms in the principal chain and up to a total of 10 carbon atoms; M is oxygen, sulfur, or NR.sub.5 ; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each independently H, lower alkyl, lower alkoxy, hydroxy, halo, trihalomethyl, hydroxy lower alkyl, carboxy, formyl, aryl, aryloxy, benzyloxy, lower alkanoyl, carboxy lower alkoxy, nitro, amino, lower alkylamino, dilower alkylamino, cyano, lower alkanoyloxy, carbamoyl, lower alkoxy-alkoxy, carbo-lower-alkoxy-alkoxy, or tetrahydropyranylmethyl; and R.sub.5 is hydrogen or lower alkyl.
A method for the treatment of hypersensitive, inflammatory or allergic conditions in a mammal, comprising the administration to said animal of a therapeutically effective amount of a compound having the following formula:
A therapeutic composition for the treatment of hypersensitive, inflammatory or allergic conditions comprising as an active ingredient an effective amount of a compound of a formula
Dependencies are inferred from the claim text.