Method for purfication of rabic virus
AssigneeJuridical Foundation The Chemo-Sero-Therapeutic Research Institute
InventorsKuniaki Sakamoto, Kunio Ohkuma, Tetsuo Kawahara, Mitsuo Sakoh
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Abstract
Disclosed is a method for the purification of rabic virus, which comprises subjecting a solution containing the rabic virus to column chromatography using, as a gel for chromatography, a sulfuric acid ester of cellulose or a crosslinked polysaccharide. The method can provide highly purified rabic virus which is useful for obtaining an effective vaccine against rabies.
Claims6
A method for the purification of rabic virus, which comprises subjecting a solution containing the rabic virus to column chromatography using, as a gel for chromatography, a sulfuric acid ester of cellulose or a crosslinked polysaccharide, said sulfuric acid ester being prepared by treating a gel of cellulose or crosslinked polysaccharide with a sulfating agent in an organic solvent.
Dependencies are inferred from the claim text.