A method for physiologically adjusting the pacing interval of a pacemaker, said pacemaker including means for generating an atrial pacing pulse, means for delivering the atrial pacing pulse to the atrium of the heart, means for sensing the depolarization of the atrium in response to the delivered atrial pacing pulse, means for generating a ventricular pacing pulse, means for delivering the ventricular pacing pulse to the ventricle of the heart, and means for sensing the depolarization of the ventricle, said method comprising the steps of:
- (a) generating one of said atrial or ventricular pacing pulses and delivering said pacing pulse to the appropriate chamber of the heart;
- (b) sensing the depolarization of the heart chamber to which the pacing pulse is delivered;
- (c) measuring the time interval between the generation of the specified pacing pulse and a specified sensed depolarization, said time interval comprising a depolarization time interval;
- and
- (d) adjusting the pacing interval of the pacemaker as a function of the time interval measured in step (c).