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US 4,710,565 AGranted
Thesis of 7-halo-7-deoxylincomycins
AssigneeThe Upjohn Company
InventorsDouglas A. Livingston, Janet E. Petre
Life of this patent
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Abstract
Process for preparing clindamycin and analogs thereof by reacting lincomycin or an analog thereof with a dimethylformamide and an excess of thionyl halide.
Claims15
A process for preparing a compound selected from the group consisting of 7-halo-7-deoxylincomycin and analogs thereof which comprises reacting a compound selected from the group consisting of lincomycin and analogs thereof with thionyl halide and dimethylformamide under mild conditions.
Dependencies are inferred from the claim text.