Treatment of autoimmune disorders with immunoamplifiers
AssigneeImreg, Inc.
InventorA. Arthur Gottlieb
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Abstract
Therapeutic methods for treatment of rheumatoid arthritis, lupis, Type I diabetes, and other autoimmune disorders are described wherein amplifiers of the immune system response are administered to the subject. Instead of further increasing the hyperactive immune response, however, administering the amplifiers has the effect of reducing the excessive immune responsiveness. Compositions for such administration are also described.
Claims18
A method of treating human or mammalian subjects for disorders characterized by hyperactive immune response, comprising the administration to said subject of an effective dosage amount of an amplifier of the immune system in a pharmaceutically acceptable carrier.
As an article of manufacture, an effective biweekly dosage amount of an amplifier of the immune system for the treatment of an autoimmune disorder, said dosage amount being in a pharmaceutically acceptable carrier, and said dosage amount being approximately 10.sup.5 to 10.sup.8 times the amount of said amplifier found to produce a maximal delayed type hypersensitivity response to antigen in a skin test.
A method of treating a patient for rheumatoid arthritis comprising administering to said patient, biweekly, the quantity of Amplifier Beta derived from approximately 400,000 leukocytes.
Dependencies are inferred from the claim text.