US 4,698,160 AGranted

Method and apparatus for preparing hemodialysis fluids of accurately portioned components

AssigneeToray Industries, Inc.

InventorMasato Haraguchi

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Abstract

Method and apparatus for preparing a mixed fluid of accurately portioned components for hemodialysis comprises the use of a closed receptacle of fixed volume. Two or more components for the fluid are introduced into a chamber in the closed receptacle to fill it and the resultant fluid of the portioned and mixed components is delivered from the chamber. One or more of the components is introduced into the chamber in predetermined amounts, the sum of which is insufficient to fill the whole volume of the chamber, before or during which the other component is introduced into the chamber and the other component is introduced into the chamber in an amount sufficient to fill the remaining volume of the chamber. The method and apparatus are suitable for preparing dialysate solutions for the use in hemodialysis.

Claims36

Dependent claims

In a method for preparing a mixed fluid of accurately portioned components for hemodialysis wherein at least two components are introduced into the chambers of a fixed volume closed receptacle to fill said chambers, and for delivering the resulting fluid, said receptacle having a pair of chambers separated by partition means, at least a part of which partition means is capable of being displaced to change the respective volumes of the chambers such that the amount of volume increase of one chamber is essentially identical to the corresponding volume decrease of another chamber, the steps which comprise:

a. accurately metering an amount of one or more of the fluid components by an independent means and introducing the metered fluid component(s) into one of said chambers of said receptacle,
b. introducing an unmetered amount of another of said fluid components into the same chamber of the receptacle to increase the volume of said chamber in an amount sufficient completely to fill said chamber, the unmetered amount being large in relation to the amount of said accurately metered component(s),
c. completing step (a) upon or before completion of the step (b),
d. closing a feed valve for controlling the feeding or fluid components into the increased volume chamber and then opening a delivery valve for delivering the accurately portioned fluid componenfs from the increased volume chamber in response to the completion of the displacement of the partition means,
e. alternately repeating the introduction of the fluid components into each chamber and the subsequent delivery of the accurately portioned fluid components from each said chamber, and
f. circulating the accurately portioned fluid components in a closed circuit comprising a dialysis cell and the chambers to perform hemodialysis.

3 more elements

An apparatus for preparing a mixed fluid of accurately portioned fluid components for hemodialysis which comprises:

a. at least two closed fixed-volume multi-chamber receptacles connected for receiving at least two fluid components in the same chamber, said receptacles each having at least two chambers separated by an intervening partition means, at least a part of said partition means being movable to change the respective volumes of said chambers so that one chamber is capable of increasing its volume to reach a predetermined known volume and a volume increase of one chamber is identical to a corresponding volume decrease of the other chamber;
b. a chamber feed means including at least one independent metering means upstream from said chambers for metering in a predetermined amount of one or more measured fluid components into said chambers, said amounts having a volume much less than said predetermined known volume;
c. a further feed means having no metering means connected to said the same chambers for introducing and mixing another fluid component into said chambers in a volume which is sufficient, together with the volume of said one or more metered components, to fill the entire predetermined known volume of said chambers, the amount of unmetered component(s) being large in relation to the amount of said metered component(s);
d. a feed valve for controlling the feeding of fluid components into said chambers, the feed valve being closeable in response to the completion of the displacement of the partition means;
e. a delivery valve for controlling the delivery of the accurately portioned fluid components from the chambers, the delivery valve being openable in response to both (i) the completion of the displacement of the partition means and (ii) the closin of the feed valve;
and
f. a closed circuit comprising a dialysis cell connected to said receptacles to form a closed circuit in which the accurately portioned fluid components alternately delivered from the receptacles is circulated to perform hemodialysis.

4 more elements

Dependencies are inferred from the claim text.

Facts

Application: 06/680,248Filed 11 Dec 1984 · continuation
Priority: 25 Feb 1980
Granted: 6 Oct 1987
Term ends: Not estimatedThe source records don’t support an estimate.

Classification11 codes

G05D 11/001
Control of flow ratio: with discontinuous action
A61M 1/1639
With volume chamber balancing devices between used and fresh dialysis fluid: linked by membranes
A61M 1/1656
Dialysates therefor: apparatus for preparing dialysates
B01F 23/49
Mixing liquids with liquids; Emulsifying: mixing systems, i.e. flow charts or diagrams