Vector encoding hepatitis B surface antigen
AssigneeIntegrated Genetics, Inc.
InventorsRenee A. Fitts, Nancy Hsiung, Dean H. Hamer
Life of this patent
Estimating the term…
Abstract
Recombinant DNA vector including (1) a promoter for a eukaryotic metalliothionein gene ligated to a gene sequence encoding hepatitis B surface antigen, and (2) at least the 69% transforming region of the bovine papilloma genome, expression of the hepatitis B surface antigen encoding gene sequence being under the control of the metallothionein promoter.
Claims11
A recombinant DNA vector comprising (1) a promoter for a eukaryotic metallothionein gene ligated to a gene sequence encoding human hepatitis B surface antigen, and (2) at least the 69% transforming region of the bovine papilloma virus genome, expression of said hepatitis B surface antigen encoding gene sequence being under the control of said metallothionein promoter.
A mammalian cell transformed with a recombinant DNA vector comprising (1) a promoter for a eukaryotic metallothionein gene ligated to a gene sequence encoding human hepatitis B surface antigen, and (2) at least the 69% transforming region of the bovine papilloma virus genome, expression of said hepatitis B surface antigen encoding gene sequence being under the control of said metallothionein promoter.
A cell exhibiting the characteristics of the cells assigned ATCC Accession No. CRL 8399.
A plasmid exhibiting the characteristics of the transforming plasmid incorporated into the cells assigned ATCC Accession No. CRL 8399.
Dependencies are inferred from the claim text.