Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same

Abstract

A compound of the formula: ##STR1## wherein R.sup.1 is hydrogen, R.sup.2 is hydrogen, lower alkyl, ar(lower)alkyl, lower alkenyl or aryl, R.sup.3 is lower alkyl, ar(lower)alkyl, lower alkenyl or aryl, or R.sup.2 and R.sup.3 are taken together to form (C.sub.2 -C.sub.6)-alkylidene group optionally substituted with aryl or taken together with the attached nitrogen atom to form a saturated or unsaturated, 5- or 6-membered heterocyclic group optionally substituted with aryl or lower alkyl; or R.sup.1 and R.sup.2 are taken together with the attached nitrogen atoms to form a saturated or unsaturated, 5- or 6-membered heterocyclic group or 1,2-diazaspiroalkane-1,2-diyl group, R.sup.3 is hydrogen, lower alkyl, ar(lower)alkyl, lower alkenyl or aryl; R.sup.4 is lower alkyl optionally substituted with di(lower)alkylamino or a heterocyclic group, or a heterocyclic group optionally having suitable substituent(s), R.sup.5 is hydrogen or lower alkyl, and X is O or S, and a pharmaceutically acceptable salt thereof may be used as anti-inflammatory and analgesic agents.

Dependencies are inferred from the claim text.