2-(2-pyridylmethylthio (sulfinyl)) benzimidazoles
AssigneeTakeda Chemical Industries, Ltd.
InventorsAkira Nohara, Yoshitaka Maki
Life of this patent
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Abstract
The compound of the formula ##STR1## wherein R.sup.1 is hydrogen, methoxy or trifluoromethyl, R.sup.2 and R.sup.3 are independently hydrogen or methyl, R.sup.4 is a C.sub.2-5 fluorinated alkyl and n denotes 0 or 1, or a pharmacologically acceptable salt thereof is novel, and useful for prophylaxis and therapy of digestive ulcers (e.g. gastric ulcer, duodenal ulcer) and gastritis.
Claims10
A phramaceutical composition for preventing or treating digestive ulcers or gastritis, which contains an effective amount of a compound of the formula ##STR8## wherein R.sup.1 is hydrogen, methoxy or trifluoromethyl, R.sup.2 and R.sup.3 are independently hydrogen or methyl, R.sup.4 is a C.sub.2-5 fluorinated alkyl and n denotes 0 or 1, or a pharmacologically acceptable salt thereof, and pharmacologically acceptable carriers.
A method for preventing or treating digestive ulcers or gastritis, which comprises administering a compound of the formula ##STR9## wherein R.sup.1 is hydrogen, methoxy or trifluoromethyl, R.sup.2 and R.sup.3 are independently hydrogen or methyl, R.sup.4 is a C.sub.2-5 fluorinated alkyl and n denotes 0 or 1, or a pharmacologically acceptable salt thereof, and pharmacologically acceptable carriers.
Dependencies are inferred from the claim text.