Thermoplastic polyurethane anticoagulant alloy coating
AssigneeDeseret Medical, Inc.
InventorsCharles W. McGary, Donald D. Solomon
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Abstract
An antithrombogenic thermoplastic polyurethane product and process for preparing the same which comprises a substrate and at least one layer of a polyurethane alloy complex comprising a thermoplastic polyurethane and completely dispersed therein a preformed complex of an antithrombogenic material ionically bonded with a quaternary ammonium compound.
Claims15
A thermoplastic polyurethane product possessing long-term antithrombogenic and antibiotic properties, comprising
- (a) a polyurethane alloy complex formed in a solvent solution;
- (b) said polyurethane alloy complex including
- (1) a thermoplastic polyurethane;
- (2) a material dispersed throughout said thermoplastic polyurethane;
- (3) said dispersed material being selected from the group consisting of an antithrombogenic material, an antibiotic material, and mixtures thereof;
- (4) said dispersed material ionically bonded to said thermoplastic polyurethane by a quaternary ammonium compound;
- (c) a solid polyurethane substrate separate from said thermoplastic polyurethane in said polyurethane alloy complex comprised of a material not soluble in said solvent solution for said polyurethane alloy complex;
- and
- (d) said polyurethane alloy complex being in the form of a surface layer on said separate polyurethane substrate.
A method for producing a thermoplastic polyurethane product possessing long-term antithrombogenic and antibiotic properties, comprising the steps of
- (a) selecting a thermoplastic polyurethane;
- (b) selecting a material from the group consisting of an antithrombogenic material, an antibiotic material and mixtures thereof;
- (c) selecting a quaternary ammonium compound;
- (d) coupling said material from step (b) with said quaternary ammonium compound from step (c);
- (e) adding said thermoplastic polyurethane from step (a), and said material from step (d) to an organic solvent solution;
- (f) dispersing said material from step (d) throughout said material from step (a) to form a polyurethane alloy complex solution;
- (g) selecting a solid article comprised of a polyurethane not soluble in said organic solvent solution from step (b);
- (h) coating the surface of said solid article from said fourth selecting step with said solution from step (f);
- and
- (i) removing said solvent solution from the coated surface formed in step (h) to form a solid substrate of said article comprised of polyurethane having disposed on the surface thereof a layer of an alloy complex including polyurethane separate from the polyurethane in said article.
Dependencies are inferred from the claim text.