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US 4,676,898 AGranted
Chromatography column using horizontal flow
AssigneeSepragen Corporation
InventorVinit Saxena
Life of this patent
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AssigneeSepragen Corporation
InventorVinit Saxena
Estimating the term…
A chromatographic column is disclosed in which flow through the separating medium bed takes place horizontally. The column is packed with small, rigid, high performance separation medium. The fluid sample containing several components flows horizontally through the stationary phase or medium and is separated at least partially into discrete components. Means for providing even horizontal flow distribution of the sample fluid and for collection of the discrete components of the sample fluid are included. The stationary phase consists of a packed bed of high performance, small size particles of either (a) absorbants such as silica, alumina etc; (b) packing for reverse phase ion-exchange, affinity, hydrophobic, chiral or ion chromatography; (c) hydroxylapatite; or packing used for desalting. The column as a whole may be fabricated to be disposable or may be constructed to have a more simplified but durable housing.
A chromatography column utilizing horizontal flow of sample material passing therethrough comprising:
In a chromatographic column having a housing defining a chamber therein and a pair of removable end sections, a pair of porous frits positioned in spaced coaxial relation within said chamber, a core member located within a first of said pair of porous frits, and a bed of chromatographic separation material positioned in said chamber intermediate said pair of porous frits, the improvement comprising:
Dependencies are inferred from the claim text.