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US 4,665,188 AGranted
Certain [(1-imidazolyl)-lower-alkylene]-tetrahydronaphthalenecarboxylic acids or corresponding idan-carboxylic acids which are thromboxane A.sub.2
AssigneeDaiichi Seiyaku Co., Ltd.
InventorMunefumi Kanao
Life of this patent
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Abstract
Benzocycloalkane derivatives of the formula (I) ##STR1## wherein: Z represents a methylene group or an ethylene group, either one of R.sup.1 and R.sup.2 represents --(CH.sub.2).sub.m --COOR.sup.3 and the other represents ##STR2## wherein R.sup.3 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, n represents an interger of 1 to 6 and m represents an interger of 0 to 5, and the physiologically acceptable salts thereof; having a strong and selective inhibition activity of thromboxane A.sub.2 synthesis.
Claims8
A compound of the formula (I) ##STR37## wherein:
- Z represents a methylene group or an ethylene group, either one of R.sup.1 and R.sup.2 represents --(CH.sub.2).sub.m --COOR.sup.3 and the other represents ##STR38## wherein R.sup.3 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, n represents an integer of 1 to 6 and m represents an integer of 0 to 5, and the physiologically acceptable salt thereof.
Dependencies are inferred from the claim text.