Cycloalkane-indene-carboximidamide derivatives
AssigneeAkzo N.V.
InventorTom Beetz
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Abstract
The present invention is dealing with cycloalkane-indene-carboximidamide derivatives having the general formula: ##STR1## wherein Rx together with either Ry.sub.1 or Ry.sub.2 represent the moiety ##STR2## (the other Ry being hydrogen), n represents the number 1, 2 or 3, R represents hydrogen or a (1-4 C)-alkyl group, R.sub.1 represents hydrogen, (1-4 C)-alkyl, hydroxyl, (1-4 C)-alkoxy or an amino group which is unsubstituted or substituted by (1-4 C)-alkyl and R.sub.2 is hydrogen, hydroxyl or (1-4 C)-alkyl, as well as the pharmaceutically acceptable salts thereof, with powerful blood platelet aggregation-inhibiting activity.
Claims5
A compound of the formula:
- ##STR10## wherein Rx together with either Ry.sub.1 or Ry.sub.2 represent the moiety ##STR11## (the other Ry being hydrogen), n represents the number 1, 2 or 3,
- R represent hydrogen or a (1-4 C)-alkyl group,
- R.sub.1 represents hydrogen, (1-4 C)-alkyl, hydroxyl, (1-4 C)-alkoxy or an amino group which is unsubstituted or substituted by (1-4 C)-alkyl and
- R.sub.2 is hydrogen, hydroxyl or (1-4 C)-alkyl, as well as the pharmaceutical acceptable salts thereof.
Dependencies are inferred from the claim text.