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US 4,650,788 AGranted
Novel peptides having an immunostimulating action, processes for their preparation and their use
AssigneeHoechst Aktiengesellschaft
InventorsHorst Kessler, Bernhard Kutscher, Rainer Obermeier, Hubert Mullner
Life of this patent
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Abstract
The invention relates to cyclopeptides of the formula I ##STR1## in which A denotes Lys, D-Lys, Arg or D-Arg, B denotes Lys, D-Lys, Arg or D-Arg, C denotes Asp, D-Asp, Glu or D-Glu, U denotes Val or D-Val and D denotes Tyr, D-Tyr, Trp, D-Trp, Phe or D-Phe, 1 to 4 of the radicals A, B, C, U and D being in the L-configuration and the remaining radicals being in the D-configuration, processes for their preparation, their use and peptidic precursors and processes for their preparation.
Claims8
A cyclopeptide of the formula I ##STR10## in which A denotes Lys, D-Lys, Arg or D-Arg,
- B denotes Lys, D-Lys, Arg or D-Arg,
- C denotes Asp, D-Asp, Glu or D-Glu,
- U denotes Val or D-Val and
- D denotes Tyr, D-Tyr, Trp, D-Trp, Phe or D-Phe, 1 to 4 of the radicals A, B, C, U and D being in the L-configuration and the remainder being in the D-configuration, and a physiologically acceptable salt thereof.
1 more element
Dependencies are inferred from the claim text.