US 4,645,858 AGranted

Pentanedioic acid derivatives

AssigneeG. D. Searle & Co.

InventorsHarman S. Lowrie, John S. Baran

Life of this patent

Estimating the term…

Abstract

Compounds of formula I are described which are useful to inhibit the formation of serum cholesterol by virtue of their ability to inhibit .beta.-hydroxy-.beta.-methylglutaryl-CoA(HMG CoA), the rate-controlling substance in the synthesis of serum cholesterol.

Claims4

Dependent claims

A compound of the formula ##STR28## wherein R.sub.1, R.sub.2, and R.sub.3 are methyl and

n is an integer from 10 to 12 inclusive.

Dependencies are inferred from the claim text.

Facts

Application: 06/786,027Filed 10 Oct 1985 · continuation
Priority: 22 Mar 1982
Granted: 24 Feb 1987
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

C07C 59/31
Containing ether groups, [IMAGE cpc-sch-C07C-0958.gif] groups,[IMAGE cpc-sch-C07C-0959.gif] groups, or[IMAGE cpc-sch-C07C-0960.gif] groups:…
C07C 33/20
Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part: monocyclic
C07C 57/26
Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms: containing rings other than six-membered aromatic rings
C07C 59/245
Saturated compounds containing more than one carboxyl group: containing hydroxy or O-metal groups

Family

Serial360,543Parent of this continuation-in-part · filed 22 Mar 1982
Serial577,411Parent of this continuation · filed 6 Feb 1984
US 4,645,858 AThis patent

From the US filing history. Foreign family members aren’t listed.

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