Novel organic trithio oxides and method for the preparation thereof
AssigneeThe Research Foundation of State University of New York
InventorsEric Block, Saleem Ahmad
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AssigneeThe Research Foundation of State University of New York
InventorsEric Block, Saleem Ahmad
Estimating the term…
This invention relates to novel organic trithio oxides of the formula: R.sup.1 --X --R--X.sup.1 --R.sup.1 wherein R is selected from --CH.sub.2 CH.dbd.CH--, ##STR1## and (CH.sub.2).sub.3 ; X is selected from ##STR2## X.sup.1 is selected from --S--S, ##STR3## and, each R.sup.1 is independently selected from carboxyalkyl, alkoxy, alkylthio, amino, alkylamino and acyl substituted and unsubstituted lower alkyl, lower alkenyl, lower alkynyl, phenyl and lower alkylphenyl; provided when R is --CH.sub.2 CH.dbd.CH--, X is ##STR4## and X.sup.1 is --S--S--, then R.sup.1 is not in both instances --CH.sub.2 CH.dbd.CH.sub.2. This invention also relates to a method of preparing the above-identified compounds by heating and further oxidizing various oxides of organic disulfides and to antithrombotic uses of the compounds.
A compound of the formula:
A method of inhibiting the aggregation of blood platelets, comprising applying thereto a blood platelet aggregation inhibiting amount of at least one compound of the formula:
Dependencies are inferred from the claim text.