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US 4,640,931 AGranted
3-(indian-5-yloxy (or thio)) cyclopentanecarboxylic acid analogues
AssigneeOno Pharmaceutical Co., Ltd.
InventorsKatsuhiro Imaki, Tadao Okegawa, Yoshinobu Arai
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Abstract
The present invention relates to novel compounds of the general formula: ##STR1## wherein X represent an oxygen atom or a sulfur atom and R represents a hydrogen atom or an alkyl group of 1-4 carbon atoms, and non-toxic salts thereof when R represents a hydrogen atom, possessing an inhibitory effect on cerebral edema.
Claims7
A 3-(indan-5-yloxy (or thio))cyclopentanecarboxylic acid analogue of the general formula:
- ##STR21## wherein X represents an oxygen atom or a sulfur atom and R represents a hydrogen atom or an alkyl group of 1-4 carbon atoms;
- or a non-toxic salt thereof when R represents a hydrogen atom.
A composition for treating cerebral edema which comprises an effective amount of a 3-(indan-5-yloxy (or thio)cyclopentanecarboxylic acid analogue of the general formula:
- ##STR22## wherein X represents an oxygen atom or a sulfur atom and R represents a hydrogen atom or an alkyl group of 1-4 carbon atoms;
- or a non-toxic salt thereof when R represents a hydrogen atom and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.