Inactivation of viruses in labile blood derivatives
AssigneeNew York Blood Center, Inc.
InventorBernard Horowitz
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Abstract
There is disclosed a process for obtaining a protein-containing composition which is substantially free of lipid-containing viruses without incurring substantial protein denaturation comprising contacting said protein-containing composition with an effective amount of oleic acid, its ester or alkali or alkaline earth metal salt for a sufficient period of time to inactivate virus contained therein.
Claims24
A process for rendering a blood product which comprises a labile protein substantially free of lipid-containing viruses without incurring substantial protein denaturation comprising contacting said product with an effective amount of C.sub.1 -C.sub.4 -alkyl oleic acid, its ester or alkali or alkaline earth metal salt thereof for a sufficient period of time to inactivate virus contained therein.
Dependencies are inferred from the claim text.