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US 4,591,442 AGranted
Flash chromatography
AssigneeNelson Research & Development Company
InventorRobert S. Andrews
Life of this patent
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AssigneeNelson Research & Development Company
InventorRobert S. Andrews
Estimating the term…
A flash chromatography apparatus and method for rapid, moderate-resolution separation of organic compounds. A solvent reservoir is pressurized with a gas, forcing solvent under pressure through tubing into and through a sorbent-packed chromatography column. More than one solvent reservoir may be provided to permit mixed-solvent elution. Alternatively, instead of pressurizing the solvent with compressed air, one or more metering pumps may be used to deliver solvent to the column. The method includes introducing a sample to be eluted into the top of a flash chromatography column, beginning elution by introducing an elution solvent under pressure into the top of the column, the elution solvent comprising a first solvent and a second solvent in a ratio from 0:1 to 1:0, modifying the elution solvent by varying the ratio of the first solvent to the second solvent, and continuing elution with the modified elution solvent.
A flash chromatography apparatus, comprising:
A flash chromatography apparatus, comprising:
In a method for performing flash chromatography, comprising the steps of:
Dependencies are inferred from the claim text.