Method for treating metabolic bone disease in mammals
AssigneeWisconsin Alumni Research Foundation
InventorsHector F. DeLuca, Heinrich K. Schnoes
Life of this patent
Estimating the term…
Abstract
A method for treating or preventing metabolic bone disease characterized by loss of bone mass in mammals by administering 24-epi-1.alpha.,25-dihydroxy vitamin D.sub.2 alone or in combinations thereof with bone mobilization-inducing vitamin D derivatives to said mammals.
Claims18
A method for preventing or treating physiological disorders in mammals, which disorders are characterized by a requirement to regenerate or prevent loss of bone mass, which comprises administering to said mammals an amount of 1 alpha,25-dihydroxy-24-epi vitamin D.sub.2 sufficient to induce mineralization of bone and thereby to increase or prevent loss of net bone mass.
A pharmaceutical composition comprising 1.alpha.,25-dihydroxy-24-epi vitamin D.sub.2 and a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.