Process in the purification of biologically active substances
AssigneePharmacia Corporation
InventorsSture J. Gustafsson, Per O. Hedman, Torbjorn G. I. Ling, Bo G. Mattiasson
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Abstract
The invention is concerned with purification of a biologically active substance with the aid of a system of at least two immiscible aqueous phases; the process of the invention involves binding said substance to particles which have an affinity for said substance and distribute predominantly quantitative into one of said phases, and subsequently liberating said substance from said particles after separating the particle-containing phase from the other phase or the other phases.
Claims6
In a process for the purification of a biologically active substance with the aid of a system of at least two immiscible aqueous phases, the improvement that said substance is caused to bind to insoluble particles which have an affinity for said substance and distribute predominantly quantitative into one of said phases, and after separating the particle-containing phase from the other phase or the other phases, said substance is liberated from said particles.
Dependencies are inferred from the claim text.