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US 4,565,819 AGranted
Substituted imino diacids, their preparation and pharmaceutical compositions which contain them
AssigneeAdir
InventorsMichel Vincent, Georges Remond, Michel Laubie
Life of this patent
Estimating the term…
Abstract
Compounds of the general formula: ##STR1## wherein: the ring A is saturated and n=0 or 1, or the ring A is a benzene ring and n=1, R.sub.1 represents a lower alkyl group which can carry an amino group, R.sub.2 represents a hydrogen atom or a lower alkyl group, R.sub.3 represents a straight or branched alkyl group, a mono- or di-cycloalkylalkyl or phenylalkyl group having no more than a total of 9 carbon atoms, or a substituted alkyl group, and also the salts thereof. These compounds are useful as therapeutic drugs.
Claims9
Compounds having the general formula:
- ##STR20## wherein the ring A is saturated and n=1,
- R.sub.1 represents a lower alkyl group having from 1 to 4 carbon atoms which can carry an amino group,
- R.sub.2 represents a hydrogen atom or an alkyl group having from 1 to 4 carbon atoms,
- R.sub.3 represents a straight or branched alkyl group, a monoor di-cycloalkylalkyl group having no more than a total of 9 carbon atoms, or a substituted alkyl group of the formula:
- ##STR21## with R.sub.4 =H, a lower alkyl (C.sub.1 to C.sub.4) or a cycloalkyl (C.sub.3 to C.sub.6) group,
- R.sub.5 32 H, a lower alkyl (C.sub.1 to C.sub.4), a cycloalkyl (C.sub.3 to C.sub.6) or an alkoxycarbonyl group,
- Y=S or >N-Q where Q=H, or an acetyl or benzyloxycarbonyl group,
- and
- p=1 or 2, and
- a=0 or 1
- in their racemic form or as optical isomers, and the salts thereof obtained with a therapeutically compatible inorganic or organic base, or their addition salts obtained with a pharmaceutically compatible inorganic or organic acid.
8 more elements
Dependencies are inferred from the claim text.