Process for producing biotin-vitamers
AssigneeNippon Zeon Co., Ltd.
InventorsHideaki Yamada, Yoshiki Tani, Yoshikazu Izumi
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Abstract
In a process which comprises cultivating a micro-organism having the ability to produce a biotin-vitamer in a culture medium in the presence of a biotin-vitamer precursor thereby to produce the biotin-vitamer and accumulate it in the culture medium, the improvement wherein the biotin-vitamer precursor is added to the culture medium after the microbial cells have been grown.
Claims4
In a process which comprises cultivating a strain of the genus Bacillus having the ability to produce a biotin-vitamer in a nutrient-containing culture medium in the presence of pimelic acid thereby to produce the biotin-vitamer and accumulate it in the culture medium, the improvement wherein pimelic acid is added to the culture medium one to two days after the starting of the cultivation.
Dependencies are inferred from the claim text.