# US 4,557,935 A · Germicidal composition

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- Number: US 4,557,935 A
- Document ID: US4557935A
- Status: Granted
- Kind: A
- Application number: 06/613,207
- Filed: 1984-05-23
- Granted: 1985-12-10
- Earliest claimed: 1981-03-17
- Assignees: Biogram AB
- Inventors: Bo T. af Ekenstam; Per-Olof Glantz; Kare Larsson
- Web page: https://patentgrep.com/patent/US4557935A

## CPC

- A01N 25/22: containing ingredients stabilising the active ingredients
- A01N 59/00: Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A61K 8/22: Peroxides; Oxygen; Ozone
- A61K 8/375: {the alcohol moiety containing more than one hydroxy group}
- A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)}
- A61P 17/00: Drugs for dermatological disorders
- A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61Q 15/00: Anti-perspirants or body deodorants (deodorisation of air A61L9/00)
- A61Q 17/005: {Antimicrobial preparations}
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

A germicidal composition consists of an aqueous suspension of hydrophilic lipid crystals of 1-monolaurin, and preferably also 1-monomyristin, in a quantity of 20-30 percent by weight, and hydrogen peroxide in a quantity of 0.2-5 percent by weight. The hydrophilic lipid crystals stabilize the hydrogen peroxide, to the effect that the composition retains its germicidal power even after having been stored for a long time. Also, the peroxide disintegrates slowly when the composition has been applied onto skin or mucous membrane.

## Claims

### Claim 1

A germicidal composition consisting essentially of an aqueous suspension containing 20-30 percent by weight of hydrophilic lipid crystals and 0.2-5 percent by weight of hydrogen peroxide, the hydrophilic lipid crystals being 10-100 percent by weight of 1-monolaurin and 0-90 percent by weight of 1-monomyristin.

### Claim 2 (depends on 1)

The germicidal composition as claimed in claim 1, wherein the ratio of 1-monolaurin to 1-monomyristin is from 30:70 to 80:20.

### Claim 3 (depends on 1)

The germicidal composition as claimed in claim 1, further including a zinc salt.

### Claim 4 (depends on 1)

The germicidal composition as claimed in claim 1, further including an astringent agent.

### Claim 5 (depends on 1)

The germicidal composition as claimed in claim 1, further including salicylic acid.

### Claim 6 (depends on 1)

A method of treating herpes-induced ulcers comprising the application to the ulcers of a germicidal composition as claimed in claim 1.