Benzisoselenazolones and a process for the treatment of inflammatory diseases
AssigneeA. Nattermann & Cie GmbH
InventorsAndre Welter, Sigurd Leyck, Eugen Etschenberg
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Abstract
The invention relates to new benzisoselenazolones of the general formula I ##STR1## and a process for the treatment of humans suffering from inflammatory diseases of the rheumatic type.
Claims11
Benzisoselenazolones of the formula I ##STR4## wherein R.sup.1 and R.sup.2 which can be the same or different from each other, are selected from the group consisting of hydrogen, halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, hydroxyl, trifluoromethyl, nitro, di-(C.sub.1 -C.sub.4 -alkyl)-amino and R.sup.1 and R.sup.2 together, methylenedioxy, and R.sup.3 is a member selected from the group consisting of the heterocyclic group pyridyl, and such heterocyclic group substituted once or twice, identically or differently, by halogen, C.sub.1 -C.sub.2 -alkyl, C.sub.1 -C.sub.4 -alkoxy, hydroxyl, nitro, and carboxyl.
2-(2-Pyridyl)-1,2-benzisoselenazol-3(2H)-one.
2-(3-Pyridyl)-1,2-benzisoselenazol-3(2H)-one.
2-(4-Pyridyl)-1,2-benzisoselenazol-3(2H)-one.
2-(2-Chloro-3-pyridyl)-1,2-benzisoselenazol-3(2H)-one.
2-(2,6-Dichloro-3-pyridyl)-1,2-benzisoselenazol-3(2H)-one.
2-(6-Methoxy-3-pyridyl)-1,2-benzisoselenazol-3(2H)-one.
2-(5-Chloro-2-pyridyl)-1,2-benzisoselenazol-3(2H)-one.
2-(4,6-Dimethyl-2-pyridyl)-1,2-benzisoselenazol-3(2H)-one.
Dependencies are inferred from the claim text.