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US 4,544,745 AGranted
Cis-4a-aryl, 1, 2, 3, 4, 4A, 9B-hexahydro-benzofuro-[3,2-C]- pyridines useful as analgesics
AssigneeHoechst-Roussel Pharmaceuticals Inc.
InventorSolomon S. Klioze
Life of this patent
Estimating the term…
Abstract
Cis-4a-aryl, 1, 2, 3, 4, 4A, 9B-hexahydro-benzofuro-[3,2-C]- pyridines, useful as analgesic and anticonvulsant agents are described.
Claims16
A compound of the formula ##STR14## wherein A is ##STR15## X being hydrogen, halogen, methyl, methoxy or hydroxyl, halogen being fluorine, chlorine, bromine or iodine;
- and R is ethyoxycarbonyl, cyanoloweralkyl, phenylcarbonylloweralkyl, phenoxyloweralkyl, phenylacetyl or cycloalkylcarbonyl where the carbonyl group of the phenylcarbonylloweralkyl may be in the ethylene ketal form;
- and the phenyl or phenoxy group in said phenylcarbonyloweralkyl, phenoxyloweralkyl or phenylacetyl group may have a halogen attached thereto and a pharmaceutically acceptable acid addition salt of any of the foregoing.
Dependencies are inferred from the claim text.