Method of treating coccidiosis with acyl guanidines
AssigneeWilliam H. Rorer, Inc.
InventorsWilliam L. Studt, Stuart A. Dodson, Harry K. Zimmerman, James L. Barnes
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Abstract
Methods for the treatment of physiological disorders, including protozoal infections in mammalian and avian species and gastrointestinal and cardiovascular disorders in mammalian species by administering a class of aralkyl- and aralkenyl-acyl, and thioacyl, guanidine compounds, pharmaceutical compositions containing such compounds for systemic administration, and a class of novel aralkenyl-, aryl-substituted cycloalkyl-, and arylsubstituted heterocycle-acyl and thioacyl guanidines.
Claims5
A method of treating coccidiosis in poultry comprising administering to poultry infected with coccidiosis a therapeutically effective amount of a compound of the formula ##STR55## wherein:
- R.sub.1 and R.sub.2 are hydrogen, halo, lower alkoxy, trihalomethyl, and at least one of R.sub.1 and R.sub.2 are halo or trihalomethyl;
- R.sub.3 is hydrogen or methyl;
- and
- R.sub.4 is lower alkyl;
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.