Method of producing acyclovir
AssigneeBurroughs Wellcome Co.
InventorThomas A. Krenitsky
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Abstract
The novel compound 6-deoxyacyclovir is enzymatically converted to acyclovir by xanthine oxidase/dehydrogenase or aldehyde oxidase in vivo, i.e. within the body of the animal being treated. The enzymatic conversion may also be effected ex vivo (i.e. in vitro) as a method of synthesizing acyclovir.
Claims9
A method of producing acyclovir which comprises converting 6-deoxyacyclovir or a physiologically acceptable salt thereof in an aqueous liquid in the presence of oxygen and xanthine oxidase to produce said acyclovir.
A method of producing acyclovir which comprises converting 6-deoxyacyclovir or a physiologically acceptable salt thereof in an aqueous liquid in the presence of oxygen and aldehyde oxidase to produce said acyclovir.
A method of producing acyclovir which comprises converting 6-deoxyacyclovir or a physiologically acceptable salt thereof in an aqueous liquid in the presence of oxygen and xanthine dehydrogenase to produce said acyclovir.
Dependencies are inferred from the claim text.