Nucleotide enriched humanized milk and process for its preparation

Nucleotide enriched humanized milk in liquid form which comprises:

• cow's milk;
• demineralized whey;
• vegetable oils;
• lactose;
• dipotassium phosphate;
• tripotassium citrate;
• sodium ascorbate;
• vitamins;
• minerals;
• and all of the following nucleotides in the precise ratios cited:
• AMP (adenosine-monophosphate) 1.7 mg/liter, CMP (cytidine-monophosphate) 1.5 mg/liter, GMP (guanosine-monophosphate) 1.9 mg/liter, UMP (uridine-monophosphate) 4.4 mg/liter and IMP (inosine-monophosphate) 0.6 mg/liter.

A process for the preparation of a nucleotide enriched humanized milk in powder form comprising cow's milk;

• demineralized whey;
• vegetable oils;
• lactose;
• dipotassium phosphate;
• tripotassium citrate;
• sodium ascorbate;
• vitamins;
• minerals;
• and all of the following nucleotides in the precise ratios cited:
• AMP (adenosine-monophosphate) 1.32 mg/100 g, CMP (cytidine-monophosphate) 1.12 mg/100 g, GMP (guanosine-monophosphate) 1.49 mg/100 g, UMP (uridine-monophosphate) 3.42 mg/100 g and IMP (inosine-monophosphate) 0.45 mg/100 g, said process comprising the steps of:
• forming a lactose solution by dissolving lactose in water of low saline content, by means of a high speed stirrer;
• adjusting the pH of said solution to about 7.5 with potassium hydroxide;
• preparing a mixture of cow's milk, water, and minerals;
• mixing said mixture with said lactose solution;
• spreading demineralized whey on said lactose solution, and said mixture, said spreading being conducted in a slow and gradual manner;
• adding a mixture of vegetable oils to said whey-containing mixture and emulsifying said vegetable oils in said whey-containing mixture;
• pre-heating said emulsified mixture containing vegetable oils;
• homogenizing under pressure, pasteurizing and evaporating said pre-heated mixture containing vegetable oils;
• adding nucleotides to said homogenized, pasteurized and evaporated mixture;
• drying said mixture containing nucleotides by means of a spray-drier to obtain a dry base;
• mixing said dry base with a further portion of lactose in powder form;
• and
• adding vitamins to said mixture of base and lactose to obtain a final dry powder product.

A process for the preparation, in liquid form, of a nucleotide enriched humanized milk comprising cow's milk;

• demineralized whey;
• vegetable oils;
• lactose;
• dipotassium phosphate;
• tripotassium citrate;
• sodium ascorbate;
• vitamins;
• minerals, and all of the following nucleotides in the precise ratios cited:
• AMP (adenosine-monophosphate) 1.7 mg/liter, CMP (cytidine-monophosphate) 1.5 mg/liter, GMP (guanosine-monophosphate) 1.9 mg/liter, UMP (uridine-monophosphate) 4.4 mg/liter and IMP (inosine-monophosphate) 0.6 mg/liter, said process comprising, in the following order, the steps of:
• forming a lactose solution by dissolving lactose in water and adjusting the pH with potassium hydroxide;
• preparing a mixture of cow's milk, water, vitamins and minerals;
• mixing said lactose solution with said cow's milk mixture;
• spreading demineralized whey on said lactose solution and said cow's milk mixture;
• emulsifying a mixture of vegetable oils into said whey-containing mixture;
• pre-heating and homogenizing said emulsified mixture, said homogenizing being followed by a first sterilization and a cooling;
• adding nucleotides to said cooled mixture;
• bottling said nucleotide containing solution in high density polyethylene bottles;
• and
• sterilizing said bottled solution a second time to obtain a final product in liquid form.