Polymeric compositions and hydrogels formed therefrom
AssigneeSyntex (U.S.A.) Inc.
InventorsPaul M. Gallop, Donald R. Korb
Life of this patent
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Abstract
The invention provides new hydrogel forming materials comprising synthetic, hydrophilic, aqueous-insoluble polymer networks formed by copolymerization of a hydrophilic dihydroxyalkyl acrylate or methacrylate, a substantially water insoluble alkyl acrylate or methacrylate, one or more additional hydrophilic comonomers selected from the group of vinylic monomers, acrylates, and methacrylates, and a cross-linking agent. The hydrogels are preferably used for the formation of contact lenses, but may also be used for drug and pesticides delivery devices; dialysis, ultrafiltration and reverse osmosis membranes; implants in surgery and dentistry; and the like.
Claims16
A hydrogel formed from a hydrophilic polymer comprising:
- a first monomer comprising a hydrophilic compound having the formula:
- ##STR10## wherein:
- R is hydrogen or methyl;
- and
- n is an integer from 1 to 4;
- a second monomer comprising a substantially insoluble acrylate or methacrylate selected from the group consisting of methyl acrylate, methyl methacrylate, ethyl acrylate, ethyl methacrylate, propyl acrylate, propyl methacrylate, isopropyl acrylate, isopropyl methacrylate, butyl acrylate and butyl methacrylate;
- and
- a third monomer selected from the group consisting of vinyl acetate, 3-buten-1-ol, 2-propen-1-ol, 5-hexenol, methyl vinyl ether, propyl vinyl ether, butyl 3-buten-1-ol ether, N-methyl vinyl amide, N-propyl vinyl amide, N-ethyl-3-butenzmide, vinyl pyrrolidone, 3-hydroxypropyl acrylate, 2-hydroxyethyl acrylate, 2-hydroxyethyl methacrylate, methacrylamide, N-methyl methacrylamide, N-N-dimethyl methacrylamide, and mixtures thereof.
Dependencies are inferred from the claim text.