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US 4,543,339 AGranted
Early pregnancy detection by detecting enhanced blood platelet activation
OwnerChristopher O'Neillinventor
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Abstract
A method and reagent system for detecting pregnancy in a mammal at an early stage by detecting enhanced activation of blood platelets.
Claims15
A method of detecting pregnancy in a mammal at an early stage shortly following conception which comprises detecting enhanced activation of blood platelets.
A system for detecting pregnancy in a mammal at an early stage by latex agglutination which comprises:
- (a) a polystyrene latex suspension,
- (b) an anticoagulant,
- (c) a source of multivalent ions, and
- (d) an inhibitor for preventing non-pregnancy-specific platelet activation.
1 more element
A system for detecting pregnancy in a mammal at an early stage by platelet adhesion, which comprises:
- (a) a substrate of a glass or plastics material,
- (b) a fixative for fixing adherent platelets to the substrate,
- (c) a labelled antibody to detect the presence of platelets adhering to the substrate, and
- (d) a macromolecular source to prevent non-pregnancy specific binding to the substrate.
1 more element
Dependencies are inferred from the claim text.