5-[Phenylsulfonyl(or sulfinyl)]thiophene-2-sulfonamides for the topical treatment of elevated intraocular pressure
AssigneeMerck & Co., Inc.
InventorKenneth L. Shepard
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Abstract
5-[Phenylsulfonyl(or sulfinyl)]thiophene-2-sulfonamides are useful for the topical treatment of elevated intraocular pressure. Ophthalmic compositions including drops and inserts are disclosed.
Claims9
An ophthalmic composition for the topical treatment of glaucoma and ocular hypertension comprising a solid water soluble polymer and from 0.1 to 35% by weight of the carbonic anhydrase inhibitor 5-[(4-hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide.
A method for treating elevated intraocular pressure which comprises topically applying to an eye in need of such treatment, an effective intraocular pressure lowering amount of the carbonic anhydrase inhibitor, 5-[(4-hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide.
Dependencies are inferred from the claim text.