2-Oxo-3-phenyl indole derivatives, drugs having a neuroanabolic action containing them, and their use
AssigneeHoechst Aktiengesellschaft
InventorsHeinz Kuch, Hansjorg Kruse
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Abstract
Oxindole derivatives of the general formula I ##STR1## are described, and also processes for their preparation and drugs containing them. The new compounds exhibit a neuroanabolic action in various animal models.
Claims6
A compound of the formula ##STR13## in which n is 1, 2, or 3, R.sup.1, R.sup.2 and R.sup.3 are identical or different and independently of one another are hydrogen, halogen, straight-chain or branched alkyl having 1 to 4C atoms, trifluoromethyl, methylenedioxy, alkoxy having 1 to 3C atoms, or nitro, R.sup.4 and R.sup.5 are identical or different and independently of one another are hydrogen or straight-chain or branched alkyl which has 1 to 6C atoms and R.sup.6 is hydrogen, alkyl having 1 to 5C atoms or hydroxyl with the proviso that R.sub.1, and R.sub.2 and R.sub.3 together are not trinitro or di- or tri-adjacent t-butyl.
The compound which is (1H-2,3-dihydro-2-oxo-3-phenyl-indolyl)-acetamide having a structural formula ##STR14##
Dependencies are inferred from the claim text.