Compound having vasodilating, antiaggregating and hypocholesterolemic activities, process for the preparation thereof and pharmaceutical compositions therefrom
AssigneeEdmond Pharma s.r.l.
InventorGuido Vandoni
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Abstract
The compound having formula (I) ##STR1## is obtained by reacting 1,2-diphenyl-4-[2-phenylsulfinyl)-ethyl]-4-hydroxymethyl-pyrazolidine-3,5- dione (hydroxymethylsulfinpyrazone) with nicotinic acid, in the presence of activating agents such as DCCD. (I) is endowed with marked vasodilating, antiaggregating and hypocholesterolemic properties.
Claims3
1,2-D iphenyl-4-[2-(phenylsulfinyl)ethyl]-4-(nicotinoyloxymethyl)-pyrazolidine-3, 5-dione, having formula (I):
- ##STR4##
A pharmaceutical composition having vasodilating, antiaggregating and hypocholesterolemic activity which contain an effective amount of compound (I) as the active principle and at least one pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.