Antidiabetic salicylic acid derivatives
AssigneeHoechst Aktiengesellschaft
InventorsVolker Hitzel, Rudi Weyer, Karl Geisen, Harald Ritzel
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Abstract
Salicylic acid derivatives of the formula I ##STR1## wherein R.sup.1, W, X, Y and Z have the meanings indicated or a physiologically tolerated salt thereof, processes for their preparation, pharmaceutical formulations based on these compounds and their use as antidiabetic agents.
Claims4
A salicylic acid derivative of the formula I ##STR11## in which W denotes a carboxyl group or an alkoxycarbonyl group having up to 4 carbon atoms in the alkoxy moiety, Z denotes a hydrogen atom or a halogen atom, R.sup.1 denotes a hydrogen atom, a (C.sub.1 -C.sub.6)-alkyl group, a (C.sub.2 -C.sub.6)-alkenyl group or an alkoxyalkyl group having a total of up to 6 carbon atoms, Y denotes an alkylene radical having 1-3 C atoms, X denotes a pyridine radical of the formula II ##STR12## wherein R.sup.2 denotes a hydrogen atom or a halogen atom or an alkyl group having up to 4 C atoms or an alkoxy group having up to 4 C atoms in the alkoxy moiety, R.sup.3 denotes a hydrogen atom or an alkyl group having up to 4 C atoms, A denotes a (C.sub.4 to C.sub.8)-alkyleneimino group, which is unsubstituted or substituted by one or two (C.sub.1 -C.sub.4)-alkyl groups, this group being bonded to the rest of the molecule via the nitrogen atom, or a physiologically tolerated salt with an acid or a base.
Dependencies are inferred from the claim text.