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US 4,542,101 AGranted
Process for the cultivation of matrix-bound biologic cell systems
OwnerStephan Neesinventor
Life of this patent
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Abstract
Improved process for cultivation of matrix-bound biologic cell systems on microcarrier particles within a replenishable nutrient medium including the step of providing controlled three dimensional displacement of a culture vessel and its contents to effect uniform cell exposure to available nutrient material.
Claims6
Process for the cultivation of matrix-bound biologic cell systems on microcarrier particles in a nutrient medium which is confined in a culture vessel, comprising the steps of imparting to the culture vessel and its contents a back-and-forth movement about a first axis;
- simultaneously imparting to the culture vessel a back-and-forth rotary movement about a second axis;
- and freshening the nutrient medium by oxygenation.
Dependencies are inferred from the claim text.