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US 4,542,096 AGranted
Detecting rearranged human c-myc DNA fragments associated with oncogenes
AssigneePresident and Fellows of Harvard College
InventorPhilip Leder
Life of this patent
Estimating the term…
Abstract
Rearranged DNA fragments associated with oncogenes are detected by DNA hybridization to a labelled probe comprising DNA fragment subject to rearrangement.
Claims3
The method of detecting rearranged human c-myc DNA fragments associated with oncogenes in a biological sample which comprises
- immobilizing DNA from sample cells and from normal control cells on solid supports
- subjecting said immobilized DNA to hybridization with a labelled fragment of human c-myc DNA subject to chromosomal rearrangement in malignant cells to determine whether rearrangement is present in said sample cells.
Dependencies are inferred from the claim text.