15,16 -Methylene-17.alpha.-pregna-4,6-diene-21-carboxylic acid salts, pharmaceutical preparations containing them and a process for their production
AssigneeSchering Corporation
InventorsKlaus Nickisch, Dieter Bittler, Henry Laurent, Rudolf Wiechert, Wolfgang Losert
Life of this patent
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Abstract
New 15,16-methylene-17.alpha.-pregna-4,6-diene-21-carboxylic acid salts of formula I ##STR1## wherein R.sup.1 and R.sup.2 each alone is hydrogen or together they form an additional CC bond or a methylene group, M is an alkali metal, and the methylene group in the 15,16 position is in the .alpha. or .beta. position, in addition to having a strong antialdosterone effect, have reduced antiandrogenic and progestogenic side effects.
Claims15
A 15,16-methylene-17.alpha.-pregna-4,6-diene-21-carboxylic acid salt of the formula ##STR4## wherein R.sup.1 and R.sup.2 each is hydrogen or together they form an additional CC bond or a methylene group,
- M is an alkali metal,
- and the methylene group in the 15,16 position is in the .alpha. or .beta. position.
Dependencies are inferred from the claim text.