Back to results
US 4,541,956 AGranted
Tin steroids and their use as antineoplastic agents
AssigneeUnique Technologies, LLC
InventorsNathan F. Cardarelli, Sebastian V. Kanakkanatt
Life of this patent
Estimating the term…
Abstract
A method and composition for the preparation of steroid compounds by the reaction of various organotin compounds with steroids. Said compounds retard the growth of malignant tumors and, in some cases, completely destroy the tumor.
Claims3
A tin steroid compound,
- said tin steroid compound being the reaction product of a steroid compound and a tin compound, wherein said steroid compound is selected from the group consisting of cholic acid, testosterone, deoxycholic acid, cholesteryl chloride, cholesterol, and dehydroxycholesterol, and ##STR19## wherein R.sub.1, R.sub.2 and R.sub.3 can be the same or different, wherein said R.sub.1, R.sub.2 and R.sub.3 are selected from the group consisting of hydrogen, an alkyl having from 1 to 6 carbon atoms, a cycloalkyl having from 4 to 10 carbon atoms, an aromatic or an alkyl substituted aromatic having from 6 to 12 carbon atoms, and an aromatic substituted alkyl having from 7 to 12 carbon atoms, and wherein X is selected from the group consisting of hydroxyl, halide, hydroxide oxide wherein R.sub.2 and R.sub.3 do not exist, a dicarboxylic acid having from 2 to 10 carbon atoms, and a monocarboxylic acid having from 2 to 6 carbon atoms.
Dependencies are inferred from the claim text.