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US 4,540,806 AGranted
Benzocycloalkane amines
AssigneeAmerican Home Products Corporation
InventorsMeier E. Freed, Magid A. Abou-Gharbia
Life of this patent
Estimating the term…
Abstract
Benzocycloalkane amine derivatives and their non-toxic acid addition salts as novel analgesic agents.
Claims9
A compound of the formula ##STR6## in which R is alkoxy of 1 to 6 carbon atoms, hydroxy, alkanoyloxy of 2 to 6 carbon atoms, aralkoxy of 7 to 12 carbon atoms;
- R.sub.1 is alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, or phenylalkyl of 7 to 12 carbon atoms;
- R.sub.2 is hydrogen, alkyl of 1 to 6 carbon atoms or phenylalkyl of 7 to 12 carbon atoms;
- R.sub.3 is hydrogen, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, hydroxy, phenylalkyl of 7 to 12 carbon atoms or alkanoyl of 2 to 6 carbon atoms;
- X is hydrogen, oxygen or hydroxy;
- n is one of the integers 2, 3, 4, 5 or 6;
- the dotted lines represent unsaturation between the cycloalkyl ring and X when X is oxygen and within the cycloalkyl ring when X is hydrogen;
- or a pharmaceutically acceptable salt thereof.
4 more elements
Dependencies are inferred from the claim text.