Thiocyanatoquinoxaline compounds with immunomodulating activity
AssigneeNorwich Eaton Pharmaceuticals, Inc.
InventorRobert J. Alaimo
Life of this patent
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Abstract
New thiocyanatoquinoxaline compounds useful as immunomodulating agents which have the general formula: ##STR1## wherein R is hydrogen, methyl or 5-thiocyanato-2-furanyl; R.sub.1 is hydrogen, methyl or 2-furanyl; or R and R.sub.1 taken together completes a cyclohexyl ring.
Claims11
A compound of the formula:
- ##STR3## wherein R is hydrogen, methyl or 5-thiocyanato-2-furanyl;
- R.sub.1 is hydrogen, methyl or 2-furanyl;
- or R and R.sub.1 taken together with the atoms to which they are attached form a cyclohexyl ring.
A method for mitigating the immunological incompetence of a host which comprises administering to a host in need of such treatment an effective amount of a pharmaceutical composition comprising a compound of the formula:
- ##STR4## wherein R is hydrogen, methyl, or 5-thiocyanato-2-furanyl;
- R.sub.1 is hydrogen, methyl or 2-furanyl;
- or R and R.sub.1 taken together with the atoms to which they are attached form a cyclohexyl ring.
A pharmaceutical composition useful as an immunomodulating agent, comprising as active ingredient an effective amount of a compound of the formula:
- ##STR5## wherein R is hydrogen, methyl or 5-thiocyanato-2-furanyl;
- R.sub.1 is hydrogen, methyl or 2-furanyl;
- or R and R.sub.1 taken together with the atoms to which they are attached form a cyclohexyl ring;
- with a pharmaceutically acceptable carrier or adjuvant.
Dependencies are inferred from the claim text.